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The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury

Traumatic brain injury (TBI) is the leading cause of death in young adults in the United States, but there is still no effective agent for treatment. N-arachidonoylethanolamine (anandamide, AEA) is a major endocannabinoid in the brain. Its increase after brain injury is believed to be protective. Ho...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Tchantchou, Flaubert, Tucker, Laura B., Fu, Amanda H., Bluett, Rebecca J., McCabe, Joseph T., Patel, Sachin, Zhang, Yumin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437642/
https://ncbi.nlm.nih.gov/pubmed/24937045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.06.006
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