The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice

BACKGROUND AND PURPOSE: Inflammatory pain presents a problem of clinical relevance and often elicits allodynia, a condition in which non-noxious stimuli are perceived as painful. One potential target to treat inflammatory pain is the endogenous cannabinoid (endocannabinoid) system, which is comprise...

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Detalhes bibliográficos
Main Authors: Booker, Lamont, Kinsey, Steven G, Abdullah, Rehab A, Blankman, Jacqueline L, Long, Jonathan Z, Ezzili, Cyrine, Boger, Dale L, Cravatt, Benjamin F, Lichtman, Aron H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Themed Section: Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423256/
https://ncbi.nlm.nih.gov/pubmed/21506952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01445.x
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