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Pancreatic Tumorigenesis: Oncogenic KRAS and the Vulnerability of the Pancreas to Obesity

SIMPLE SUMMARY: Pancreatic cancer is a devastating disease with a poor survival rate, and oncogenic mutant KRAS is a major driver of its initiation and progression; however, effective strategies/drugs targeting major forms of mutant KRAS have not been forthcoming. Of note, obesity is known to worsen...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Luo, Yongde, Li, Xiaokun, Ma, Jianjia, Abbruzzese, James L., Lu, Weiqin
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918840/
https://ncbi.nlm.nih.gov/pubmed/33668583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040778
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