PRKAR1B-AS2 Long Noncoding RNA Promotes Tumorigenesis, Survival, and Chemoresistance via the PI3K/AKT/mTOR Pathway

Many long noncoding RNAs have been implicated in tumorigenesis and chemoresistance; however, the underlying mechanisms are not well understood. We investigated the role of PRKAR1B-AS2 long noncoding RNA in ovarian cancer (OC) and chemoresistance and identified potential downstream molecular circuitr...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Elsayed, Abdelrahman M., Bayraktar, Emine, Amero, Paola, Salama, Salama A., Abdelaziz, Abdelaziz H., Ismail, Raed S., Zhang, Xinna, Ivan, Cristina, Sood, Anil K., Lopez-Berestein, Gabriel, Rodriguez-Aguayo, Cristian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918312/
https://ncbi.nlm.nih.gov/pubmed/33668685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041882
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