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Blockade of CDK7 Reverses Endocrine Therapy Resistance in Breast Cancer

Cyclin-dependent kinase (CDK)-7 inhibitors are emerging as promising drugs for the treatment of different types of cancer that show chemotherapy resistance. Evaluation of the effects of CDK7 inhibitor, THZ1, alone and combined with tamoxifen is of paramount importance. Thus, in the current work, we...

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Publicat a:Int J Mol Sci
Autors principals: Attia, Yasmin M., Shouman, Samia A., Salama, Salama A., Ivan, Cristina, Elsayed, Abdelrahman M., Amero, Paola, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215326/
https://ncbi.nlm.nih.gov/pubmed/32340192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082974
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