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Blockade of CDK7 Reverses Endocrine Therapy Resistance in Breast Cancer

Cyclin-dependent kinase (CDK)-7 inhibitors are emerging as promising drugs for the treatment of different types of cancer that show chemotherapy resistance. Evaluation of the effects of CDK7 inhibitor, THZ1, alone and combined with tamoxifen is of paramount importance. Thus, in the current work, we...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Attia, Yasmin M., Shouman, Samia A., Salama, Salama A., Ivan, Cristina, Elsayed, Abdelrahman M., Amero, Paola, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215326/
https://ncbi.nlm.nih.gov/pubmed/32340192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082974
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