Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPARα‐FGF21 Axis

The fatty acid desaturase 1 (FADS1), also known as delta‐5 desaturase (D5D), is one of the rate‐limiting enzymes involved in the desaturation and elongation cascade of polyunsaturated fatty acids (PUFAs) to generate long‐chain PUFAs (LC‐PUFAs). Reduced function of D5D and decreased hepatic FADS1 exp...

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Bibliografske podrobnosti
izdano v:Hepatol Commun
Main Authors: Athinarayanan, Shaminie, Fan, Yang‐Yi, Wang, Xiaokun, Callaway, Evelyn, Cai, Defeng, Chalasani, Naga, Chapkin, Robert S., Liu, Wanqing
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917273/
https://ncbi.nlm.nih.gov/pubmed/33681679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1629
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