Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPARα‐FGF21 Axis

The fatty acid desaturase 1 (FADS1), also known as delta‐5 desaturase (D5D), is one of the rate‐limiting enzymes involved in the desaturation and elongation cascade of polyunsaturated fatty acids (PUFAs) to generate long‐chain PUFAs (LC‐PUFAs). Reduced function of D5D and decreased hepatic FADS1 exp...

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Enregistré dans:
Détails bibliographiques
Publié dans:Hepatol Commun
Auteurs principaux: Athinarayanan, Shaminie, Fan, Yang‐Yi, Wang, Xiaokun, Callaway, Evelyn, Cai, Defeng, Chalasani, Naga, Chapkin, Robert S., Liu, Wanqing
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917273/
https://ncbi.nlm.nih.gov/pubmed/33681679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1629
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