Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPARα‐FGF21 Axis

The fatty acid desaturase 1 (FADS1), also known as delta‐5 desaturase (D5D), is one of the rate‐limiting enzymes involved in the desaturation and elongation cascade of polyunsaturated fatty acids (PUFAs) to generate long‐chain PUFAs (LC‐PUFAs). Reduced function of D5D and decreased hepatic FADS1 exp...

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Dettagli Bibliografici
Pubblicato in:Hepatol Commun
Autori principali: Athinarayanan, Shaminie, Fan, Yang‐Yi, Wang, Xiaokun, Callaway, Evelyn, Cai, Defeng, Chalasani, Naga, Chapkin, Robert S., Liu, Wanqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917273/
https://ncbi.nlm.nih.gov/pubmed/33681679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1629
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