The Non-peptide Angiotensin-(1–7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats

Delayed neurocognitive recovery (dNCR) after surgery is a common postoperative complication in older adult patients. Our previous studies have demonstrated that cognitive impairment after surgery involves an increase in the brain renin-angiotensin system (RAS) activity, including overactivation of t...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Mi, Xinning, Cao, Yiyun, Li, Yue, Li, Yitong, Hong, Jingshu, He, Jindan, Liang, Yaoxian, Yang, Ning, Liu, Taotao, Han, Dengyang, Kuang, Chongshen, Han, Yongzheng, Zhou, Yang, Liu, Yajie, Shi, Chengmei, Guo, Xiangyang, Li, Zhengqian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917118/
https://ncbi.nlm.nih.gov/pubmed/33658918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.624387
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