Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice

Delayed neurocognitive recovery (dNCR) is a major complication after anesthesia and surgery in older adults. Alpha-synuclein (α-syn; encoded by the gene, SNCA) has recently been shown to play an important role in hippocampus-dependent working memory. Aggregated forms of α-syn are associated with mul...

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Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Li, Yue, Yuan, Yi, Li, Yitong, Han, Dengyang, Liu, Taotao, Yang, Ning, Mi, Xinning, Hong, Jingshu, Liu, Kaixi, Song, Yanan, He, Jindan, Zhou, Yang, Han, Yongzheng, Shi, Chengmei, Yu, Shun, Zou, Peng, Guo, Xiangyang, Li, Zhengqian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181110/
https://ncbi.nlm.nih.gov/pubmed/34194605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5572899
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