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Genome-scale perturbation of lncRNA expression using CRISPR interference
CRISPR-mediated interference (CRISPRi), a robust and specific system for programmably repressing transcription, provides a versatile tool for systematically characterizing the function of long non-coding RNAs (lncRNAs). When used with highly parallel, lentiviral pooled screening approaches, CRISPRi...
Shranjeno v:
| izdano v: | Methods Mol Biol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7917014/ https://ncbi.nlm.nih.gov/pubmed/33326085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-1158-6_20 |
| Oznake: |
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