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Anticancer Therapy with HDAC Inhibitors: Mechanism-Based Combination Strategies and Future Perspectives

SIMPLE SUMMARY: Beyond mutations, epigenetic changes have been described as drivers for cancer as well. While leaving the overall DNA structure intact, they can be responsible for tumor malignancy by mediating the transcriptional upregulation of oncogenes. This provides the basis for “epigenetic the...

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Publicat a:Cancers (Basel)
Autors principals: Jenke, Robert, Reßing, Nina, Hansen, Finn K., Aigner, Achim, Büch, Thomas
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915831/
https://ncbi.nlm.nih.gov/pubmed/33562653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040634
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