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Thermo-Responsive PLGA-PEG-PLGA Hydrogels as Novel Injectable Platforms for Neuroprotective Combined Therapies in the Treatment of Retinal Degenerative Diseases

The present study aims to develop a thermo-responsive-injectable hydrogel (HyG) based on PLGA-PEG-PLGA (PLGA = poly-(DL-lactic acid co-glycolic acid); PEG = polyethylene glycol) to deliver neuroprotective agents to the retina over time. Two PLGA-PEG PLGA copolymers with different PEG:LA:GA ratios (1...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: López-Cano, José Javier, Sigen A., Andrés-Guerrero, Vanessa, Tai, Hongyun, Bravo-Osuna, Irene, Molina-Martínez, Irene Teresa, Wang, Wenxin, Herrero-Vanrell, Rocío
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915560/
https://ncbi.nlm.nih.gov/pubmed/33562265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020234
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