Neuroprotective effect of insulin-loaded chitosan nanoparticles/PLGA-PEG-PLGA hydrogel on diabetic retinopathy in rats

BACKGROUND: To pursuit effective sustained release systems for insulin to treat diabetic retinopathy (DR), a novel insulin delivering system was developed via loading onto chitosan nanoparticles/poly(lactic-co-glycolic acid)-poly(ethylene glycol)-poly(lactic-co-glycolic acid) hydrogel (ICNPH). METHO...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Rong, Xianfang, Ji, Yinghong, Zhu, Xiangjia, Yang, Jin, Qian, Dongjin, Mo, Xiaofen, Lu, Yi
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302824/
https://ncbi.nlm.nih.gov/pubmed/30587984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S184574
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