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Depletion of Cholesteryl Esters Causes Meibomian Gland Dysfunction-Like Symptoms in a Soat1-Null Mouse Model

Previous studies on ablation of several key genes of meibogenesis related to fatty acid elongation, omega oxidation, and esterification into wax esters have demonstrated that inactivation of any of them led to predicted changes in the meibum lipid profiles and caused severe abnormalities in the ocul...

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Foilsithe in:Int J Mol Sci
Main Authors: Butovich, Igor A., Wilkerson, Amber, Yuksel, Seher
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915537/
https://ncbi.nlm.nih.gov/pubmed/33557318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041583
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