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Depletion of Cholesteryl Esters Causes Meibomian Gland Dysfunction-Like Symptoms in a Soat1-Null Mouse Model

Previous studies on ablation of several key genes of meibogenesis related to fatty acid elongation, omega oxidation, and esterification into wax esters have demonstrated that inactivation of any of them led to predicted changes in the meibum lipid profiles and caused severe abnormalities in the ocul...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Butovich, Igor A., Wilkerson, Amber, Yuksel, Seher
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915537/
https://ncbi.nlm.nih.gov/pubmed/33557318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041583
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