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Depletion of Cholesteryl Esters Causes Meibomian Gland Dysfunction-Like Symptoms in a Soat1-Null Mouse Model

Previous studies on ablation of several key genes of meibogenesis related to fatty acid elongation, omega oxidation, and esterification into wax esters have demonstrated that inactivation of any of them led to predicted changes in the meibum lipid profiles and caused severe abnormalities in the ocul...

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Pubblicato in:Int J Mol Sci
Autori principali: Butovich, Igor A., Wilkerson, Amber, Yuksel, Seher
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915537/
https://ncbi.nlm.nih.gov/pubmed/33557318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041583
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