Novel Use of PLGA Microspheres to Create an Animal Model of Glaucoma with Progressive Neuroretinal Degeneration

Progressive degeneration of neuroretinal tissue with maintained elevated intraocular pressure (IOP) to simulate chronic glaucoma was produced by intracameral injections of poly (lactic-co-glycolic) acid (PLGA) microspheres (Ms) in rat eyes. The right eye of 39 rats received different sizes of PLGA-M...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Garcia-Herranz, David, Rodrigo, Maria Jesus, Subias, Manuel, Martinez-Rincon, Teresa, Mendez-Martinez, Silvia, Bravo-Osuna, Irene, Bonet, Aina, Ruberte, Jesus, Garcia-Feijoo, Julian, Pablo, Luis, Garcia-Martin, Elena, Herrero-Vanrell, Rocío
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915113/
https://ncbi.nlm.nih.gov/pubmed/33567776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020237
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