Novel Use of PLGA Microspheres to Create an Animal Model of Glaucoma with Progressive Neuroretinal Degeneration

Progressive degeneration of neuroretinal tissue with maintained elevated intraocular pressure (IOP) to simulate chronic glaucoma was produced by intracameral injections of poly (lactic-co-glycolic) acid (PLGA) microspheres (Ms) in rat eyes. The right eye of 39 rats received different sizes of PLGA-M...

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Bibliografiset tiedot
Julkaisussa:Pharmaceutics
Päätekijät: Garcia-Herranz, David, Rodrigo, Maria Jesus, Subias, Manuel, Martinez-Rincon, Teresa, Mendez-Martinez, Silvia, Bravo-Osuna, Irene, Bonet, Aina, Ruberte, Jesus, Garcia-Feijoo, Julian, Pablo, Luis, Garcia-Martin, Elena, Herrero-Vanrell, Rocío
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915113/
https://ncbi.nlm.nih.gov/pubmed/33567776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020237
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