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The Structure, Activation and Signaling of IRE1 and Its Role in Determining Cell Fate

Inositol-requiring enzyme type 1 (IRE1) is a serine/threonine kinase acting as one of three branches of the Unfolded Protein Response (UPR) signaling pathway, which is activated upon endoplasmic reticulum (ER) stress conditions. It is known to be capable of inducing both pro-survival and pro-apoptot...

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Bibliografische gegevens
Gepubliceerd in:Biomedicines
Hoofdauteurs: Siwecka, Natalia, Rozpędek-Kamińska, Wioletta, Wawrzynkiewicz, Adam, Pytel, Dariusz, Diehl, J. Alan, Majsterek, Ireneusz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914947/
https://ncbi.nlm.nih.gov/pubmed/33562589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020156
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