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Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells

Altered lacrimal gland (LG) secretion is a feature of autoimmune dacryoadenitis in Sjögren’s syndrome (SS). Cathepsin S (CTSS) is increased in tears of SS patients, which may contribute to disease. Rab3D and Rab27a/b isoforms are effectors of exocytosis in LG, but Rab27a is poorly studied. To invest...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fu, Runzhong, Edman, Maria C., Hamm-Alvarez, Sarah F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914720/
https://ncbi.nlm.nih.gov/pubmed/33562815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041630
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