Gel-Free 3D Tumoroids with Stem Cell Properties Modeling Drug Resistance to Cisplatin and Imatinib in Metastatic Colorectal Cancer

Researchers have developed several three-dimensional (3D) culture systems, including spheroids, organoids, and tumoroids with increased properties of cancer stem cells (CSCs), also called cancer-initiating cells (CICs). Drug resistance is a crucial issue involving recurrence in cancer patients. Many...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Sogawa, Chiharu, Eguchi, Takanori, Namba, Yuri, Okusha, Yuka, Aoyama, Eriko, Ohyama, Kazumi, Okamoto, Kuniaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914642/
https://ncbi.nlm.nih.gov/pubmed/33562088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020344
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