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State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps

The eukaryotic chaperonin TRiC/CCT plays a major role in assisting the folding of many proteins through an ATP-driven allosteric cycle. Recent structures elucidated by cryo-electron microscopy provide a broad view of the conformations visited at various stages of the chaperonin cycle, including a se...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Prog Biophys Mol Biol
Prif Awduron: Zhang, Yan, Krieger, James, Mikulska-Ruminska, Karolina, Kaynak, Burak, Sorzano, Carlos Oscar S., Carazo, José-María, Xing, Jianhua, Bahar, Ivet
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914283/
https://ncbi.nlm.nih.gov/pubmed/32866476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2020.08.006
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