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Temporal parameters of enhanced opioid reward after initial opioid exposure in rats

RATIONALE: Mu opioid receptor agonists are indispensable for the treatment of pain, but clinical use carries the inherent risk of transition from effective treatment to abuse. Abuse potential appears to increase rapidly during periods of initial opioid exposure in humans, and this increase in opioid...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Moerke, Megan J., Negus, S. Stevens
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914195/
https://ncbi.nlm.nih.gov/pubmed/33410983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-020-05725-3
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