Llwytho...

Dissociable effects of the kappa opioid receptor agonist nalfurafine on pain/itch-stimulated and pain/itch-depressed behaviors in male rats

RATIONALE: Nalfurafine is a G-protein-signaling-biased kappa opioid receptor (KOR) agonist approved in Japan for second-line treatment of uremic pruritus. Neither nalfurafine nor any other KOR agonist is currently approved anywhere for treatment of pain, but recent evidence suggests that G-protein-s...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Psychopharmacology (Berl)
Prif Awduron: Lazenka, Matthew F., Moerke, Megan J., Townsend, E. Andrew, Freeman, Kevin B., Carroll, F. Ivy, Negus, S. Stevens
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750069/
https://ncbi.nlm.nih.gov/pubmed/29063139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4758-7
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