Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation

Corneal neovascularization (CNV) causes higher-order aberrations, corneal edema, ocular inflammation, and corneal transplant rejection, thereby decreasing visual acuity. In this study, we investigated the effects of topical administration of the kappa opioid receptor agonist nalfurafine (TRK-820) on...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shokirova, Hurramhon, Inomata, Takenori, Saitoh, Tsuyoshi, Zhu, Jun, Fujio, Kenta, Okumura, Yuichi, Yanagawa, Ai, Fujimoto, Keiichi, Sung, Jaemyoung, Eguchi, Atsuko, Miura, Maria, Nagino, Ken, Hirosawa, Kunihiko, Kuwahara, Mizu, Akasaki, Yasutsugu, Nagase, Hiroshi, Murakami, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060258/
https://ncbi.nlm.nih.gov/pubmed/33883646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88118-6
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