SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites

Glucocorticoid receptor (GR) is an essential transcription factor (TF), controlling metabolism, development and immune responses. SUMOylation regulates chromatin occupancy and target gene expression of GR in a locus-selective manner, but the mechanism of regulation has remained elusive. Here, we ide...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Paakinaho, Ville, Lempiäinen, Joanna K, Sigismondo, Gianluca, Niskanen, Einari A, Malinen, Marjo, Jääskeläinen, Tiina, Varjosalo, Markku, Krijgsveld, Jeroen, Palvimo, Jorma J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913686/
https://ncbi.nlm.nih.gov/pubmed/33524141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab032
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados