Identification and characterization of heteroclitic peptides in TCR-binding positions with improved HLA-binding efficacy

The antigenicity as well as the immunogenicity of tumor associated antigens (TAAs) may need to be potentiated in order to break the immunological tolerance. To this aim, heteroclitic peptides were designed introducing specific substitutions in the residue at position 4 (p4) binding to TCR. The effec...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Transl Med
Main Authors: Cavalluzzo, Beatrice, Ragone, Concetta, Mauriello, Angela, Petrizzo, Annacarmen, Manolio, Carmen, Caporale, Andrea, Vitagliano, Luigi, Ruvo, Menotti, Buonaguro, Luigi, Tagliamonte, Maria
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2021
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913412/
https://ncbi.nlm.nih.gov/pubmed/33637105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02757-x
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla