IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation

Primary Effusion Lymphoma (PEL) is a highly aggressive B cell lymphoma associated with Kaposi’s Sarcoma-associated Herpesvirus (KSHV). It is characterized by a high level of basal Endoplasmic Reticulum (ER) stress, Unfolded Protein Response (UPR) activation and constitutive phosphorylation of oncoge...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Gonnella, Roberta, Gilardini Montani, Maria Saveria, Guttieri, Luisa, Romeo, Maria Anele, Santarelli, Roberta, Cirone, Mara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912693/
https://ncbi.nlm.nih.gov/pubmed/33513694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020118
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