Protein Binder (ProBi) as a New Class of Structurally Robust Non-Antibody Protein Scaffold for Directed Evolution

Engineered small non-antibody protein scaffolds are a promising alternative to antibodies and are especially attractive for use in protein therapeutics and diagnostics. The advantages include smaller size and a more robust, single-domain structural framework with a defined binding surface amenable t...

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Veröffentlicht in:Viruses
Hauptverfasser: Pham, Phuong Ngoc, Huličiak, Maroš, Biedermannová, Lada, Černý, Jiří, Charnavets, Tatsiana, Fuertes, Gustavo, Herynek, Štěpán, Kolářová, Lucie, Kolenko, Petr, Pavlíček, Jiří, Zahradník, Jiří, Mikulecky, Pavel, Schneider, Bohdan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911045/
https://ncbi.nlm.nih.gov/pubmed/33514045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020190
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