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Bayesian optimization for estimating the maximum tolerated dose in Phase I clinical trials
We introduce a Bayesian optimization method for estimating the maximum tolerated dose in this article. A number of parametric model-based methods have been proposed to estimate the maximum tolerated dose; however, parametric model-based methods need an assumption that dose–toxicity relationships fol...
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| Publicado no: | Contemp Clin Trials Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7910500/ https://ncbi.nlm.nih.gov/pubmed/33681528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2021.100753 |
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