The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis

Uridylation is a widespread modification destabilizing eukaryotic mRNAs. Yet, molecular mechanisms underlying TUTase-mediated mRNA degradation remain mostly unresolved. Here, we report that the Arabidopsis TUTase URT1 participates in a molecular network connecting several translational repressors/de...

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Publicado en:Nat Commun
Main Authors: Scheer, Hélène, de Almeida, Caroline, Ferrier, Emilie, Simonnot, Quentin, Poirier, Laure, Pflieger, David, Sement, François M., Koechler, Sandrine, Piermaria, Christina, Krawczyk, Paweł, Mroczek, Seweryn, Chicher, Johana, Kuhn, Lauriane, Dziembowski, Andrzej, Hammann, Philippe, Zuber, Hélène, Gagliardi, Dominique
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910438/
https://ncbi.nlm.nih.gov/pubmed/33637717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21382-2
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