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Catalytic asymmetric reductive hydroalkylation of enamides and enecarbamates to chiral aliphatic amines
To increase the reliability and success rate of drug discovery, efforts have been made to increase the C(sp(3)) fraction and avoid flat molecules. sp(3)-Rich enantiopure amines are most frequently encountered as chiral auxiliaries, synthetic intermediates for pharmaceutical agents and bioactive natu...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7910428/ https://ncbi.nlm.nih.gov/pubmed/33637730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21600-x |
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