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Enantioselective access to chiral aliphatic amines and alcohols via Ni-catalyzed hydroalkylations

Chiral aliphatic amine and alcohol derivatives are ubiquitous in pharmaceuticals, pesticides, natural products and fine chemicals, yet difficult to access due to the challenge to differentiate between the spatially and electronically similar alkyl groups. Herein, we report a nickel-catalyzed enantio...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Shan, Zhang, Jian-Xin, Zhang, Tian-Yi, Meng, Huan, Chen, Bi-Hong, Shu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119980/
https://ncbi.nlm.nih.gov/pubmed/33986269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22983-7
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