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Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes

Short QT (SQT) syndrome is a genetic cardiac disorder characterized by an abbreviated QT interval of the patient’s electrocardiogram. The syndrome is associated with increased risk of arrhythmia and sudden cardiac death and can arise from a number of ion channel mutations. Cardiomyocytes derived fro...

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Publicat a:PLoS Comput Biol
Autors principals: Jæger, Karoline Horgmo, Wall, Samuel, Tveito, Aslak
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909705/
https://ncbi.nlm.nih.gov/pubmed/33591962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008089
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