A Macrophage-Targeted Platform for Extending Drug Dosing with Polymer Prodrugs for Pulmonary Infection Prophylaxis

Pulmonary melioidosis is a bacterial disease with high morbidity and a mortality rate that can be as high as 40% in resource-poor regions of South Asia. This disease burden is linked to the pathogen’s intrinsic antibiotic-resistance and protected intracellular localization in alveolar macrophages. C...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Chavas, Thomas E. J., Su, Fang-Yi, Srinivasan, Selvi, Roy, Debashish, Lee, Brian, Lovelace-Macon, Lara, Rerolle, Guilhem F., Limqueco, Elaine, Skerrett, Shawn J., Ratner, Daniel M., West, Timothy Eoin, Stayton, Patrick S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909327/
https://ncbi.nlm.nih.gov/pubmed/33221351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.11.031
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