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Actin-Membrane Release Initiates Cell Protrusions

Despite the well-established role of actin polymerization as a driving mechanism for cell protrusion, upregulated actin polymerization alone does not initiate protrusions. Using a combination of theoretical modeling and quantitative live-cell imaging experiments, we show that local depletion of acti...

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Pubblicato in:Dev Cell
Autori principali: Welf, Erik S., Miles, Christopher E., Huh, Jaewon, Sapoznik, Etai, Chi, Joseph, Driscoll, Meghan K., Isogai, Tadamoto, Noh, Jungsik, Weems, Andrew D., Pohlkamp, Theresa, Dean, Kevin, Fiolka, Reto, Mogilner, Alex, Danuser, Gaudenz
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7908823/
https://ncbi.nlm.nih.gov/pubmed/33308479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.11.024
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