Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury

Toll-like receptor-9 (TLR-9) is a potent proinflammatory receptor that mediates renal injury. However, the reported effects of TLR-9 are contradictory. Here, using a traditional mouse AKI→CKD transition model, the roles of TLR-9 during the transition from acute kidney injury (AKI) to chronic kidney...

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Publicado en:Front Cell Dev Biol
Autores principales: Zheng, Haofeng, Zhang, Yannan, Li, Lei, Zhang, Rui, Luo, Zihuan, Yang, Zhe, Ye, Yongrong, He, Jiannan, Sun, Qiquan
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907438/
https://ncbi.nlm.nih.gov/pubmed/33644078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.641527
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