Ablation of Toll-like receptor 9 attenuates myocardial ischemia/reperfusion injury in mice

In myocardial ischemia/reperfusion injury, the innate immune and subsequent inflammatory responses play a crucial role in the extension of myocardial damage. Toll-like receptor 9 (TLR9) is a critical receptor for recognizing unmethylated CpG motifs that mitochondria contain in their DNA, and induces...

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Bibliografski detalji
Izdano u:Biochem Biophys Res Commun
Glavni autori: Kitazume-Taneike, Rika, Taneike, Manabu, Omiya, Shigemiki, Misaka, Tomofumi, Nishida, Kazuhiko, Yamaguchi, Osamu, Akira, Shizuo, Shattock, Michael J., Sakata, Yasushi, Otsu, Kinya
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590932/
https://ncbi.nlm.nih.gov/pubmed/31160091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.05.150
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