FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice

Protein quality control in cardiomyocytes is crucial to maintain cellular homeostasis. The accumulation of damaged organelles, such as mitochondria and misfolded proteins in the heart is associated with heart failure. During the process to identify novel mitochondria-specific autophagy (mitophagy) r...

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Bibliografiska uppgifter
I publikationen:J Mol Cell Cardiol
Huvudupphovsmän: Misaka, Tomofumi, Murakawa, Tomokazu, Nishida, Kazuhiko, Omori, Yosuke, Taneike, Manabu, Omiya, Shigemiki, Molenaar, Chris, Uno, Yoshihiro, Yamaguchi, Osamu, Takeda, Junji, Shah, Ajay M., Otsu, Kinya
Materialtyp: Artigo
Språk:Inglês
Publicerad: Academic Press 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807029/
https://ncbi.nlm.nih.gov/pubmed/29129702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.11.004
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