Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury

Chronic kidney disease (CKD), which is associated with high morbidity, remains a worldwide health concern, while effective therapies remain limited. Hydroxychloroquine (HCQ), which mainly targets toll-like receptor-7 (TLR-7) and TLR-9, is associated with a lower risk of incident CKD. Taking into acc...

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Vydáno v:Front Immunol
Hlavní autoři: Zheng, Haofeng, Zhang, Yannan, He, Jiannan, Yang, Zhe, Zhang, Rui, Li, Lei, Luo, Zihuan, Ye, Yongrong, Sun, Qiquan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079743/
https://ncbi.nlm.nih.gov/pubmed/33936063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.645100
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