Regulation of peripheral Th/Treg differentiation and suppression of airway inflammation by Nr4a transcription factors

Helper T (Th) and regulatory T (Treg) cell differentiation programs promote the eradication of pathogens, while minimizing adverse immune reactions. Here, we found that Nr4a family of nuclear receptors supports Treg cell induction and represses Th1 and Th2 cell differentiation from naive CD4(+) T ce...

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Bibliographic Details
Published in:iScience
Main Authors: Sekiya, Takashi, Kagawa, Shizuko, Masaki, Katsunori, Fukunaga, Koichi, Yoshimura, Akihiko, Takaki, Satoshi
Format: Artigo
Language:Inglês
Published: Elsevier 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907427/
https://ncbi.nlm.nih.gov/pubmed/33665581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102166
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