Regulation of peripheral Th/Treg differentiation and suppression of airway inflammation by Nr4a transcription factors

Helper T (Th) and regulatory T (Treg) cell differentiation programs promote the eradication of pathogens, while minimizing adverse immune reactions. Here, we found that Nr4a family of nuclear receptors supports Treg cell induction and represses Th1 and Th2 cell differentiation from naive CD4(+) T ce...

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Enregistré dans:
Détails bibliographiques
Publié dans:iScience
Auteurs principaux: Sekiya, Takashi, Kagawa, Shizuko, Masaki, Katsunori, Fukunaga, Koichi, Yoshimura, Akihiko, Takaki, Satoshi
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907427/
https://ncbi.nlm.nih.gov/pubmed/33665581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102166
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