Regulation of peripheral Th/Treg differentiation and suppression of airway inflammation by Nr4a transcription factors

Helper T (Th) and regulatory T (Treg) cell differentiation programs promote the eradication of pathogens, while minimizing adverse immune reactions. Here, we found that Nr4a family of nuclear receptors supports Treg cell induction and represses Th1 and Th2 cell differentiation from naive CD4(+) T ce...

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Bibliografske podrobnosti
izdano v:iScience
Main Authors: Sekiya, Takashi, Kagawa, Shizuko, Masaki, Katsunori, Fukunaga, Koichi, Yoshimura, Akihiko, Takaki, Satoshi
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907427/
https://ncbi.nlm.nih.gov/pubmed/33665581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102166
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