Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease

CYP3A5 is the primary CYP3A subfamily enzyme expressed in the human kidney and its aberrant expression may contribute to a broad spectrum of renal disorders. Pharmacogenetic studies have reported inconsistent linkages between CYP3A5 expression and hypertension, however, most investigators have consi...

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Publicat a:Sci Rep
Autors principals: Lidberg, Kevin A., Annalora, Andrew J., Jozic, Marija, Elson, Daniel J., Wang, Lu, Bammler, Theo K., Ramm, Susanne, Monteiro, Maria Beatriz, Himmelfarb, Jonathan, Marcus, Craig B., Iversen, Patrick L., Kelly, Edward J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907328/
https://ncbi.nlm.nih.gov/pubmed/33633318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84194-w
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