Induction of revertant fibres in the mdx mouse using antisense oligonucleotides

BACKGROUND: Duchenne muscular dystrophy is a fatal genetic disorder caused by dystrophin gene mutations that result in premature termination of translation and the absence of functional protein. Despite the primary dystrophin gene lesion, immunostaining studies have shown that at least 50% of DMD pa...

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Détails bibliographiques
Auteurs principaux: Fall, Abbie M, Johnsen, Russell, Honeyman, Kaite, Iversen, Pat, Fletcher, Susan, Wilton, Stephen D
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2006
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481566/
https://ncbi.nlm.nih.gov/pubmed/16719929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-4-3
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