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Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha

Thyroid hormone signaling plays an essential role in muscle development and function, in the maintenance of muscle mass, and in regeneration after injury, via activation of thyroid nuclear receptor alpha (THRA). A mouse model of resistance to thyroid hormone carrying a frame-shift mutation in the TH...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aguiari, Paola, Liu, Yan-Yun, Petrosyan, Astgik, Cheng, Sheue-yann, Brent, Gregory A., Perin, Laura, Milanesi, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907286/
https://ncbi.nlm.nih.gov/pubmed/33633251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84080-5
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