Thyroid Hormone Receptor Alpha Mutations Lead to Epithelial Defects in the Adult Intestine in a Mouse Model of Resistance to Thyroid Hormone

Background: The thyroid hormone triiodothyronine (T3) is critical for vertebrate development and affects the function of many adult tissues and organs. Its genomic effects are mediated by thyroid hormone nuclear receptors (TRs) present in all vertebrates. The discovery of patients with resistance to...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Bao, Lingyu, Roediger, Julia, Park, Sunmi, Fu, Liezhen, Shi, Bingyin, Cheng, Sheue-Yann, Shi, Yun-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Thyroid Economy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437623/
https://ncbi.nlm.nih.gov/pubmed/30595106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2018.0340
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