Persistent COUP-TFII Expression Underlies the Myopathy and Impaired Muscle Regeneration Observed in Resistance to Thyroid Hormone-Alpha

Myopathic changes, including muscular dystrophy and weakness, are commonly described in hypothyroid and hyperthyroid patients. Thyroid hormone signaling, via activation of thyroid nuclear receptor alpha (THRA), plays an essential role in maintaining muscle mass, function, and regeneration. A mouse m...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Aguiari, Paola, Liu, Yan-Yun, Petrosyan, Astgik, Cheng, Sheue-Yann, Brent, Gregory A, Perin, Laura, Milanesi, Anna
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
Subjects:
Steroid Hormones and Receptors
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090385/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1658
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