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Persistent COUP-TFII Expression Underlies the Myopathy and Impaired Muscle Regeneration Observed in Resistance to Thyroid Hormone-Alpha

Myopathic changes, including muscular dystrophy and weakness, are commonly described in hypothyroid and hyperthyroid patients. Thyroid hormone signaling, via activation of thyroid nuclear receptor alpha (THRA), plays an essential role in maintaining muscle mass, function, and regeneration. A mouse m...

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Bibliografiske detaljer
Udgivet i:J Endocr Soc
Main Authors: Aguiari, Paola, Liu, Yan-Yun, Petrosyan, Astgik, Cheng, Sheue-Yann, Brent, Gregory A, Perin, Laura, Milanesi, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090385/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1658
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