Persistent COUP-TFII Expression Underlies the Myopathy and Impaired Muscle Regeneration Observed in Resistance to Thyroid Hormone-Alpha

Myopathic changes, including muscular dystrophy and weakness, are commonly described in hypothyroid and hyperthyroid patients. Thyroid hormone signaling, via activation of thyroid nuclear receptor alpha (THRA), plays an essential role in maintaining muscle mass, function, and regeneration. A mouse m...

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Détails bibliographiques
Publié dans:J Endocr Soc
Auteurs principaux: Aguiari, Paola, Liu, Yan-Yun, Petrosyan, Astgik, Cheng, Sheue-Yann, Brent, Gregory A, Perin, Laura, Milanesi, Anna
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Steroid Hormones and Receptors
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090385/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1658
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