Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in App(NL-G-F), App(NL-F), and wild type mice

Epigenetic mechanisms occurring in the brain as well as alterations in the gut microbiome composition might contribute to Alzheimer’s disease (AD). Human amyloid precursor protein knock-in (KI) mice contain the Swedish and Iberian mutations (App(NL-F)) or those two and also the Arctic mutation (App(...

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Pubblicato in:Sci Rep
Autori principali: Kundu, Payel, Torres, Eileen Ruth S., Stagaman, Keaton, Kasschau, Kristin, Okhovat, Mariam, Holden, Sarah, Ward, Samantha, Nevonen, Kimberly A., Davis, Brett A., Saito, Takashi, Saido, Takaomi C., Carbone, Lucia, Sharpton, Thomas J., Raber, Jacob
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907263/
https://ncbi.nlm.nih.gov/pubmed/33633159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83851-4
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